Peptides such as Epithalon are used to control cell cycle progression by increasing telomerase activity. Many animal research studies demonstrate that it possesses unique anti-aging and anti-tumour properties. Prof. Vladimir Khavinson of the Sankt Petersburg University, Russia, created Epithalon (also known as Epitalon or Epithalone) in the late 1980s. It is the synthetic form of the tetrapeptide epithalamin, which naturally exists in the pineal gland in the human body.
For the pineal gland to perform its most essential functions, such as normalising the activity of the anterior pituitary gland and maintaining the levels of calcium, gonadotropins, and melatonin in our bodies, several feedback mechanisms are used to control its activity. Antioxidant epithalamin boosts stress resistance and reduces corticosteroid levels. It’s hard to believe that epithalon has such remarkable anti-aging and life-prolonging characteristics in diverse clinical contexts.
The way it works
Epithalon increases telomerase activity to control the cell cycle. Increasing telomerase activity has a wide range of impacts on the body because it prevents the telomeres from shortening, which is an essential part of the aging process, from deteriorating. An enzyme called Telomerase, which is found on the 3’ end of the chromosome, adds tandem repeats to preserve the length of telomeres. Proliferation may continue indefinitely if telomeres are elongated, leading to cancer. Anti-aging and cancer may be prevented by maintaining the correct length of the telomeres in the body; epithalon achieves just that.
Antioxidant effects of epithalon on aging have also been shown. Reactive oxygen species (ROS) may damage DNA, causing cellular death and mutations that lead to the creation of malignant cells. This process has been linked to the slowing of the aging process.
Additionally, it has been shown to suppress carcinogenic receptor expression and reduce metastasis in breast and colorectal cancer cells, demonstrating substantial anti-tumour actions.
The modulation of essential biomolecules like cytokines, C-reactive protein, and other acute-phase reactants by the epithalon is critical in reducing inflammation. Several diseases may be caused by an imbalance in this mechanism, including but not limited to rheumatoid arthritis, ulcerative colitis, and many more.
Reduction in aging
Telomerase activity and telomere lengthening are induced in somatic cells by Epithalon. A 33% rise in telomere elongation, a factor in aging, was seen in one research. A 12-year experiment with subjects treated with epithalon and a control group was conducted. Epithalamin treatment reduced the overall mortality by 28%. According to the findings of this research, lowering functional age and the degree of cardiovascular aging resulted in a 2-fold reduction in cardiovascular mortality. According to another research, for those given thymalin and epithalamin for six years, the death rate was 4.1% lower than in the control group.
Suppression of cancer
On the use of epithalon against cancer, there has been and continues to be a great deal of scientific investigation. Studies on breast tumours, colon carcinogenesis, and prostate cancer, to mention a few, revealed that epithalon inhibits tumour formation and proliferation. Epithalon has been demonstrated to reduce the size of tumours when applied to them. Epithalon treatment prevented tumour metastasis in mice and had oncostatin qualities, preventing cancer from spreading. Epithalon’s anti-tumour capabilities in hormone-dependent cancer have been implicated in telomerase activity, endocrine function, and immunological function. Epithalon therapy restored cellular immunity, lowered recurrence and spread of cancer, and decreased tumour size in subjects with uterine, cervix, and ovarian cancer, according to research. Buy epithalon in USA if you are a researcher.